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Trouble falling asleep, waking often or waking much earlier than planned is common during cancer treatment. Tell your team if poor sleep is affecting your day. They can look for causes such as pain, worry or medicines and help you make a plan. Persistent difficulty sleeping is called insomnia.
One treatment is cognitive behavioural therapy for insomnia, or CBT-I.
Being exhausted does not guarantee that sleep will come easily. Cancer-related fatigue and insomnia can occur together, but they are not the same problem. You may need help with both, rather than being told to rest more or stay busy until you fall asleep.
What might be disturbing your sleep?
Pain, nausea, hot flushes, itching, cough or trips to the toilet can repeatedly wake you. Worry about scans or treatment may keep thoughts active at night. Hospital routines, reduced activity and daytime sleeping can also change your sleep pattern. Medicines, including steroids, sometimes contribute.
There may be a separate sleep problem. Loud snoring, pauses in breathing reported by a partner, waking gasping or marked daytime sleepiness should be discussed. An uncomfortable urge to move the legs at rest can also disturb sleep. A sleeping tablet is not the right answer to every cause.
Tell the team whether the problem is falling asleep, staying asleep or waking too early. Explain when it began and how treatment days differ from other days. Mention existing sleep difficulties, alcohol, caffeine and any sleep remedies, including products bought without a prescription.
Start by treating symptoms that wake you
Ask whether pain relief or other symptom treatment needs adjusting. If nausea, urinary discomfort or hot flushes are the main problem, address those directly. Avoid taking extra doses of pain or sleep medicines without advice.
If a steroid seems to keep you awake, ask whether its timing can be changed safely. Some treatment schedules require specific timing, so do not move or stop it yourself. Bring the full medicine list: a medicine taken earlier in the day can still affect the night.
At home, make overnight needs easier to manage. Keep a clear, well-lit route to the bathroom and put water or prescribed items within reach. If you are unsteady, ask for help rather than rushing out of bed. The aim is to support both sleep and safety.
Keep a simple sleep record
For several days, note roughly when you went to bed, how long you felt awake, when you got up and whether you slept during the day. Include major symptoms and medicines that seemed relevant. Estimates are enough; checking the clock repeatedly can make the night more stressful.
Also record what the following day was like. Did you feel sleepy, physically drained, anxious or unable to concentrate? These differences help the team decide what to investigate. A watch or phone can offer clues, but its sleep score does not diagnose insomnia or determine how you should feel.
Bring a short summary to the appointment, such as: “I fall asleep normally but wake with pain three times, and I now nap most afternoons.” This is more useful than trying to produce a perfect record.
Everyday habits that may help
Try to get up at a fairly consistent time, including after a difficult night, within the limits of illness and treatment. Daylight and suitable daytime activity can help keep a day-night rhythm. Choose safe movement rather than exhausting yourself in an attempt to force sleep.
Reduce caffeine later in the day if it affects you, remembering tea, coffee, energy drinks and some medicines. Avoid using alcohol as a sleep aid. A quiet wind-down period, lower lighting and a comfortable room may help you settle. If news or messages leave you alert or worried, put them aside before bed.
Rest is still appropriate when you are unwell. If daytime naps are making night sleep harder, discuss shorter or earlier naps rather than trying to remain awake through severe exhaustion. A person receiving intensive treatment may need a different plan from someone who has completed treatment.
These habits support sleep, but they are not a cure for every case of insomnia. If you have followed ordinary advice and remain awake for much of the night, ask about a specific treatment rather than adding more rules.
What is CBT-I?
CBT-I is a structured treatment that helps you change sleep habits and manage thoughts that keep you awake. It can help your body learn to associate bed with sleep again. The European Society for Medical Oncology recommends CBT-I as the first treatment to consider for persistent insomnia in adults with cancer.
It may be delivered individually, in a group or through a suitable supported digital programme. A clinician can adapt it to fatigue, pain, falls risk and treatment demands. Ask who provides it locally and whether a shorter or remote version is available if regular visits are difficult.
Some programmes adjust time in bed. Do not copy a strict sleep-restriction schedule from the internet, particularly if you are very sleepy, frail or at risk of falls. The plan should be supervised and suited to your health.
Research suggests that CBT-I can improve how people rate their sleep, but the amount of benefit varies. A 2025 Cochrane review found modest improvements, but confidence in most results was low. Many participants were women treated for breast cancer, so results may not apply equally to everyone.
CBT-I remains an option to discuss, with a plan suited to your symptoms and access to care.
What if worry keeps you awake?
You might set aside a short period earlier in the evening to write down concerns and the next practical step. For example, a question for the nurse can go on tomorrow's list rather than being rehearsed repeatedly in bed. This is an optional coping idea, not a requirement to stop worrying.
Gentle breathing or a guided relaxation recording may help you settle. If an exercise feels frustrating, choose something calmer or simpler. Persistent anxiety, low mood or fear of recurrence deserves its own discussion and support. The scan-anxiety article explains some of these options.
If you are lying awake and becoming frustrated, a clinician may suggest a quiet activity outside bed until you feel sleepy. Adapt this for safety: someone weak or dizzy should not get up and walk around alone in the dark. Ask how to apply the advice safely in your circumstances.
Are sleeping medicines an option?
A clinician may sometimes prescribe a sleep medicine for a short period. The choice depends on your other medicines, breathing, age, balance and daytime alertness. Taking several medicines that cause drowsiness can increase sleepiness and the risk of falls.
Do not borrow sleeping tablets or mix them with alcohol. Products sold as antihistamine sleep aids, herbal remedies or melatonin are not automatically suitable during cancer treatment. Ask about interactions, expected benefit and how long to use a prescribed product. If you already take a sleep medicine regularly, do not stop abruptly without advice.
When should you ask for more help?
Seek review if sleep problems persist, interfere with treatment or make work, driving or daily activities unsafe. Do not wait for a fixed number of weeks before mentioning severe symptoms. If you are very sleepy during the day, avoid driving and ask about assessment.
New confusion, marked restlessness, or seeing or hearing things that are not there needs urgent medical assessment. If someone is difficult to wake, has trouble breathing or develops chest pain, seek emergency help. These are different from ordinary sleep problems.
Common questions
Should I stay in bed longer after a bad night?
Not necessarily. Much more time in bed can sometimes maintain insomnia. However, treatment-related illness may require rest. Ask for a plan that balances recovery with a stable sleep routine.
Will better sleep cure cancer fatigue?
It may help, but fatigue can have several causes and needs its own assessment. The fatigue article covers pacing, activity and treatable contributors.
What should I ask at my next visit?
“Could we check what is disturbing my sleep and whether I can access CBT-I?” Bring your medicine list and a brief account of your nights and days.
Sources and further reading
- Grassi L, et al. Insomnia in adult patients with cancer: ESMO Clinical Practice Guideline. ESMO Open. 2023;8:102047. Read source
- National Cancer Institute. Sleep Problems in People with Cancer. Read source
- National Cancer Institute. Sleep Disorders (PDQ). Patient Version. Read source
- Nissen ER, et al. Interventions for insomnia in cancer patients and survivors—a comprehensive systematic review and meta-analysis. JNCI Cancer Spectrum. 2024;8(3):pkae041. doi:10.1093/jncics/pkae041. Read source
- Cai Z, et al. Cognitive behavioural therapy for insomnia in people with cancer. Cochrane Database of Systematic Reviews. 2025;10:CD015176. doi:10.1002/14651858.CD015176.pub2. Read source
- Grassi L, et al. Anxiety and depression in adult cancer patients: ESMO Clinical Practice Guideline. ESMO Open. 2023. Read source
- Memorial Sloan Kettering Cancer Center. Caring for Someone With Delirium. Patient guidance. Read source
Medically reviewed and approved by Dr (Prof) Vijay Agarwal
Professor and Lead Consultant – Medical Oncology
